I have done it a number of times and prefer to go via Lyon not Paris, as old nelson says, it is slow and easy to get lost, the peripherique exits are not well advertised and IMO, it is really easy to take a lot longer timewise despite saving 50 odd miles. I usually drive it in one go, via Lyon on the Autorutes @90mph it takes 13 hrs +/- from Calais.

If you want to stop, in the S of France, Carcasonne is worth a visit, only a short hop off the AP7-E15 coastal motorway [A61-E80 to Tolouse] .. and it has a Formula1 hotel nearby.